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Children’s Hospital of Pittsburgh of UPMC Pulmonary Chief Elected Secretary-Treasurer of the American Thoracic Society

CELEDON_JUAN_MD_PDP_20131105_CSThe American Thoracic Society (ATS) has elected Juan C. Celedón, MD, DrPH, chief, Division of Pulmonary Medicine, Allergy and Immunology at Children’s Hospital of Pittsburgh of UPMC, as its Secretary–Treasurer for the 2017–18 term.
Dr. Celedón will then assume the role of ATS President for the 2020 21 term and notably will be the first ATS president from the University of Pittsburgh, as well as the first Latino American to serve as ATS president, in the 115-year history of the society.

“I am deeply humbled and honored to have been elected as the Secretary-Treasurer of the American Thoracic Society, arguably the leading professional society in academic pulmonary, critical care and sleep medicine worldwide,” said Dr. Celedón, Niels K. Jerne Professor of Pediatrics, University of Pittsburgh School of Medicine. “I hope to further the mission of the ATS in achieving respiratory health equality and workforce diversity, while continuing to pursue excellence in research, education and training, as well as clinical care of patients with pulmonary diseases, critical illnesses and sleep disorders.”

“On behalf of the ATS community, we wholeheartedly welcome Dr. Celedón to the elected leadership of the Society,” said David Gozal, MD, MBA, president of the ATS. “His previous achievements and recognition have clearly earned him this honor. We look forward to his future contributions to the ATS and to the field of pulmonary, critical care and sleep medicine both nationally and around the world.”

Dr. Celedón has been a member of the ATS since 1993. He received from the ATS the “Recognition Award for Scientific Accomplishments” in 2014, and was the first-ever recipient of the “Lifetime Award for Innovations in Health Equality” in 2015.

His research has focused on asthma and COPD, and on health disparities in airway diseases. His research, which has been funded by the National Institutes of Health, has been recognized with his election to the American Society for Clinical Investigation and the Association of American Physicians.

Dr. Celedón, who also serves as professor of Medicine, Epidemiology and Human Genetics at the University of Pittsburgh, will be installed as Secretary–Treasurer in May at the ATS 2017 International Conference in Washington, DC.

Founded in 1905, the American Thoracic Society is the world’s leading medical association dedicated to advancing pulmonary, critical care and sleep medicine. The Society’s 15,000 members prevent and fight respiratory disease around the globe through research, education, patient care and advocacy. The ATS publishes three journals, the American Journal of Respiratory and Critical Care Medicine, the American Journal of Respiratory Cell and Molecular Biology and the Annals of the American Thoracic Society.

For more information on Dr. Celedón, visit www.chp.edu.

Announcing Our New Co-Director of the Inflammatory Bowel Disease (IBD) Center — Sandra Kim, MD, Children’s Hospital of Pittsburgh of UPMC

PrintSandra Kim, MD, a nationally recognized expert in pediatric and adolescent inflammatory bowel disease, is the co-director of the Inflammatory Bowel Disease (IBD) Center, a part of the Division of Pediatric Gastroenterology, Hepatology, and Nutrition at Children’s Hospital of Pittsburgh of UPMC. Dr. Kim is also Associate Professor of Pediatrics at the University of Pittsburgh School of Medicine. Prior to joining Children’s Hospital, Dr. Kim was co-director of the Center for Pediatric and Adolescent Inflammatory Bowel Disease at Nationwide Children’s Hospital in Columbus, Ohio.

In Pittsburgh, Dr. Kim, along with Sapana Shah, MD, will establish the hospital’s participation in Improved Care Now, a national consortium to improve the care of children with IBD. Dr. Kim’s clinical and research interests focus on pediatric inflammatory bowel diseases, including adolescent transitioning and quality improvement in pediatric IBD and the impact of the gastrointestinal microbiota in IBD. Her research has been funded by the National Institutes of Health and the Crohn’s and Colitis Foundation of America (CCFA). She has authored numerous studies on pediatric and adolescent inflammatory bowel diseases. Dr. Kim currently serves as past chair of Pediatric Affairs and current co – chair of Government Affairs/Advocacy for the CCFA nationally. In addition, she chairs the Clinical Practice and Adolescent Transitioning committees and serves on the Physician Leadership committee and Strategy Council for Improve Care Now. Dr. Kim also is involved as a member of the Medical Advisory Board for Flying Horse Farms and on the board of Directors for the Central Ohio CCFA chapter. As a reflection of her dedication to her profession, Dr. Kim was awarded the 2011 Rosenthal Award for her leadership in patient education and advocacy by the CCFA. She also was the 2015 faculty inductee at the Ohio State University College of Medicine chapters of Gold Humanism Honor Society and Alpha Omega Alpha.

Dr. Kim is a graduate of the University of Michigan’s Inteflex (Integrated Pre-medical/Medical) Program, earning bachelors’ degrees in Biomedical Sciences and Psychology as well as her medical degree. She completed clinical training in General Pediatrics and Pediatric Gastroenterology at Texas Children’s Hospital and the Baylor College of Medicine. She was a recipient of the Outstanding Clinical Fellow Award during her GI fellowship and was on the NIH/NIDDK-funded T32 grant for her research project investigating zinc metabolism in children with IBD. After her clinical training, she pursued additional training as a post-doctoral fellow at the NIH-funded Center for GI Biology and Disease at the University of North Carolina at Chapel Hill.

American Academy of Pediatrics Webinar Series on Zika Virus featuring Amy Houtrow, MD, PhD — Jan. 10, 2017

Recognizing Microcephaly and Other Presentations of Zika Virus Syndrome
Tuesday, Jan. 10, 2 p.m. ET
Registration is required.

Dial-In Information
Phone: 844-216-1726
Conference ID: 18985179
Registration Link: https://cc.readytalk.com/r/viw68r9pls12&eom

Description
Over the past year, congenital Zika virus syndrome has captured the attention of the world because of the devastating effects it can have on infants’ development. In recognition that pediatricians (primary care providers, clinicians, and subspecialists) will require support and guidance, the American Academy of Pediatrics Webinar Series on Zika Virus Syndrome was created. During the first webinar in this series, expert speakers will provide an overview of the neurodevelopmental manifestations of congenital Zika virus syndrome. Experts will also describe how to monitor symptomatic and asymptomatic infants, including how to collaborate with specialists to ensure a continuum of care.

Speakers
Amy Houtrow, MD, PhD, MPH, FAAP
Dr Houtrow is pediatric rehabilitation medicine physician and health services researcher.  She is an Associate Professor and Vice Chair in the Department of Physical Medicine and Rehabilitation for Pediatric Rehabilitation Medicine at the University of Pittsburgh School of Medicine. She directs the Pediatric Rehabilitation Medicine Fellowship and is the Chief of Pediatric Rehabilitation Medicine Services and the Medical Director of the Rehabilitation Institute at the Children’s Hospital of Pittsburgh. Dr Houtrow’s main clinical focus is caring for children with disabling conditions to help to improve functioning and quality of life to the greatest degree possible. Her research focuses on improving how children with disabilities and their families access health care to optimize health care delivery.

Edwin Trevathan, MD, MPH, FAAP
Dr. Trevathan is a child neurologist, an epidemiologist, and a public health leader, who is internationally known for his expertise in childhood epilepsy, disorders of the developing brain, developmental disabilities, and birth defects. Trevathan is a Professor of Pediatrics and Neurology at Vanderbilt University School of Medicine, and a pediatric neurologist at the Monroe Carell Jr. Children’s Hospital at Vanderbilt. Dr Trevathan has held a number of senior leadership positions in academia and in government. He has served as Executive Vice President and Provost at Baylor University; Dean of the College for Public Health and Social Justice at Saint Louis University; Director of the Division of Pediatric and Developmental Neurology at Washington University in St. Louis, MO; and Director of the National Center on Birth Defects and Developmental Disabilities at the Centers for Disease Control and Prevention.

Additional Information
Please email DisasterReady@aap.org with any questions prior to the webinar.

 

 

Grant Awarded for National Biorepository for GUDMAP Biobank

Sunder Sims-Lucas, PhD, and Jacqueline Ho, MD, are co-investigators on a $600,000 per year grant for 5 years from the National Institutes of Health to be the national biorepository for the GenitoUrinary Development Molecular Anatomy Project (GUDMAP).

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GUDMAP is an international consortium working to generate gene expression data and transgenic mice as tools to study genitourinary development. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system.

GUDMAP data is accessible at www.gudmap.org.

Hospitalized Patients at Risk if Sodium Levels are Low

Michael Moritz, MD, explains how hospitalized patients could be at risk of weak bones, and increased infections if physicians ignore low-sodium in the body, known as hyponatremia.

Dr. Moritz is clinical director, Division of Pediatric Nephrology at Children’s Hospital of UPMC and as Professor of Pediatrics at the University of Pittsburgh School of Medicine. Dr. Moritz is an authority on sodium and water metabolism in children.

Hospitalized patients at risk if sodium levels are low – Frontiers Science Hero from Frontiers on Vimeo.

Growing Kidneys in Lymph Nodes

Carl Bates, MD, and Sunder Sims-Lucas, PhD, of the Division of Pediatric Nephrology at Children’s Hospital of Pittsburgh of UPMC, in collaboration with Eric Lagasse, PhD, of the University of Pittsburgh McGowan Institute for Regenerative Medicine, are developing a novel approach to regenerate kidney tissues.

The group has discovered that embryonic kidney fragments and isolated nephron progenitors have the potential to form perfused kidney structures when injected into mouse lymph nodes. The Bates, Sims-Lucas, and Lagasse laboratories have received a Pediatric Device Initiative Award sponsored by the Commonwealth of Pennsylvania in support of their work.

 

Children’s Hospital of Pittsburgh Experts At the 30th Annual North American Cystic Fibrosis Conference

PrintThe 30th annual North American Cystic Fibrosis Conference was held October 27-29 in Orlando. The event brought scientists, clinicians, and other healthcare professionals from around the world to share the latest ideas and advances in cystic fibrosis research, drug development, and patient care, and included posters and presentations from field-leading experts.

Several Children’s Hospital of Pittsburgh of UPMC faculty and staff presented at the conference on a number of topics including:

 

Poster: Identification of Novel Inhibitors of Ubiquitination That Improve Rescue of F508DELCFTR by VX-809

Goeckeler-Fried, Jennifer; Estabrooks, Samuel K; Chiang, Annette; Chung, Wook Joon; Ye, Zhaofeng; Denny, Rajiah Aldrin; Weissman, Allan M; Camacho, Carlos J; Sorscher, Eric J; Brodsky, Jeffrey L

Poster: Recognition of CFTR By BCL2 Associated Athnaogene 3 (BAG3): A Pathway meditating Autophagic CFTR Degradation

Mishra, Sanjay K ; Frizzell, Raymond A.

Poster: Ubiquitin-Specific Proteases 11(USP11)and 28(USP28)Regulate F508DELCFTRStability Via SUMOConjugation

Gong, Xiaoyan; DaPaula ,AnaCarina; Ahner, Annette; Frizzell, Raymond A

Poster/Workshop Presentation: Predicted Phosphorylation Site in SLC26A9 Modulates CFTR-Dependent Activity

Wang, Xiaohui; Larsen, Mads B; Frizzell, Raymond A.; Bertrand, Carol A.

Poster: Pseudomonas aeruginosa Benefits From Respiratory Viral Infection in Cystic Fibrosis

Jeffrey Melvin

Poster: Viral-Bacterial Interactions in the Paranasal Sinuses in Cystic Fibrosis

Jeffrey Melvin

Abstract: Dynamics of Staphylococcus aureus growth on airway epithelial cells

Megan R Kiedrowski

Presenting: Thursday, Oct. 27 – W06: INF/MIC: Pathogenesis of Airway Infection (speaking 10:20-10:30a)

Poster Session I (11:15a-1:45p), Friday, Oct. 28 – JIB: Junior investigators best abstract session: Basic Science (12:15-1:35p)

Poster: Dysregulation of Nutritional Immunity during Respiratory Viral Infection Promotes Pseudomonas aeruginosa Biofilm Growth

Matthew Hendricks

Poster: SIRT1 Mediates Resveratrol Inhibition of CFTR In Primary Bronchial Epithelium

Agnieszka Swiatecka-Urban, MD, FASN

Poster: TGF-β1 Upregulates Microrna- 145 To Block ∆F508-CFTR Rescue

Agnieszka Swiatecka-Urban, MD, FASN

Poster: Anti-biofilm activity and in vivo efficacy of an engineered peptide antibiotic”

Berthony Deslouches

Workshop III: CLIN: *Emerging Issues in CF Lung Transplantation

A. Faro, J. Pilewski

Poster: Infection and depressed mucociliary clearance in pediatric and adult CF patients

Corcoran TE, Locke LW, Myerburg MM, Weiner DJ, Pilewski JM

Poster: Nitrogen Back Diffusion During Multiple Breath Washout With 100% Oxygen

Weiner DJ, Pederson K, Nielson JG.

Poster: Lung Function Perception in Cystic Fibrosis

Forno E, Weiner DJ

World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition 2016

PrintThe 5th World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition (WCPGHAN) was held October 5-8, 2016 in Montreal. This event showcased state of the art science and technology in the field of pediatric gastroenterology, hepatology, and nutrition, as well as presentations and keynote speeches from experts who are leaders in their field.

The conference encompassed nine themes including:

  • IBD
  • Celiac and other GI disorders
  • Neurogastroenterology and motility
  • Endoscopy
  • Hepatology
  • Pancreatology
  • Global health
  • Nutrition and intestinal rehabilitation
  • Transplantation

Several Children’s Hospital of Pittsburgh of UPMC faculty and staff spoke at the conference on a number topics including:

Immune Tolerance and Rejection
Pharmacology (pharmaco-genetics) and immunosuppression: Past, present and future
Patrick McKiernan, MD

Steatorrhea: What if it’s not Cystic Fibrosis
Mark Lowe, MD, PhD

Acute Liver Failure – Pathogenesis and Management
Rob Squires, MD and Anil Dhawan, MD

Pancreas
Mark Lowe, MD PhD

Pancreatitis

Inflammatory Responses/ Healing in Pancreatic Injury
Sohail Husain, MD

Poster Presentations

Sterile Cerebrosprinal Fluid Ascites: A Rare Complication After Ventriculoperitoneal Shunting
James Squires, MD, and  Kristen Critelli, MD (fellow)

Clinical Variability Following Partial External Biliary Diversion In Familial Intrahepatic Cholestasis 1 Deficiency
James Squires, MD,  Robert Squires, MD, and Amy Morris, RN, CCPC

Children’s Hospital of Pittsburgh of UPMC Part of New Pennsylvania Program to Improve Behavioral Health for Kids

PrintChildren’s Hospital of Pittsburgh of UPMC’s primary care network, Children’s Community Pediatrics (CCP), has been selected by the HealthChoices managed care organizations to take part in a new program to improve behavioral health treatment for children in the state.

Ted Dallas, secretary of the Department of Human Services in Pennsylvania, announced the selection of organizations to administer behavioral health treatment through the new Telephonic Psychiatric Consultation Service Program (TiPS). The announcement was made today at Children’s Hospital, with Dallas joining Christopher Gessner, president of Children’s Hospital, and Abigail Schlesinger, MD, medical director, Community Based Services, Behavioral Science Division of Children’s Hospital.

TiPS is a new program designed to provide real-time resources to physicians seeking consultation and advice for pediatric patients with behavioral health concerns who are served by Medicaid. A physician who uses the TiPS service will have access to a child and adolescent psychiatrist to discuss treatment options and get help linking the child to appropriate treatment if services outside of primary care are deemed necessary.

CCP, through its award-winning behavioral health program, will be manning the hotline to provide telephone consultation to any physician who is prescribing behavioral health medications to kids.

“It is critical that all children, regardless of where they live, have access to quality health care services,” said Dallas. “Access to child psychiatry has been a significant problem nationwide for years. Today’s announcement means that more of our kids will have the services they need, and not just another prescription.”

“Being able to provide behavioral health services in the primary care setting was a vision of ours and something that we’ve been doing for 8 years now,” said Dr. Schlesinger. “We’re excited to partner with the state of Pennsylvania to further enhance families’ ability to access behavioral health services in our region.”

CCP will serve the 26 counties in both the Southwest and Northwest zones. The Children’s Hospital of Philadelphia will serve the Southeast zone and Penn State Children’s Hospital will serve the Northeast and Lehigh/Capital zones.

For more information, visit www.childrenspeds.com.

Children’s Hospital of Pittsburgh of UPMC Earns National Recognition as Patient-Centered Medical Home

PrintChildren’s Hospital of Pittsburgh of UPMC’s Primary Care Center, part of the Division of General Academic Pediatrics, has received Level III Patient-Centered Medical Home (PCMH) Recognition from the National Committee for Quality Assurance (NCQA) for using evidence-based, patient-centered processes that focus on highly coordinated care and long‐term, participative relationships.

The three-year recognition is based on standards aligned with joint principles of the Patient-Centered Medical Home, a model of primary care that combines teamwork and information technology to improve care, to improve patients’ experience of care and to reduce costs.

“As the pediatric office for many of Pittsburgh’s underserved children, we are dedicated to providing the highest quality of care to the children in our region who are in need. This national recognition demonstrates our comprehensive approach and ongoing commitment to patient-centered care,” said Stacey Cook, MD, PhD, physician, General Academic Pediatrics, Children’s Hospital. “We provide increased access, implement quality improvement measures and provide continuing outreach to our families each and every day.”

Medical homes foster ongoing partnerships between patients, their families and their personal clinicians, instead of approaching care as the sum of episodic office visits. Each patient’s care is overseen by clinician-led care teams that coordinate treatment across the health care system.

“NCQA Patient-Centered Medical Home Recognition raises the bar in defining high-quality care by emphasizing access, health information technology and coordinated care focused on patients,” said NCQA President Margaret E. O’Kane. “Recognition shows that Children’s Hospital of Pittsburgh of UPMC has the tools, systems and resources to provide its patients with the right care, at the right time.”

NCQA standards are aligned with the joint principles of the Patient-Centered Medical Home established with the American College of Physicians, the American Academy of Family Physicians, the American Academy of Pediatrics and the American Osteopathic Association.

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