UPMC Physician Resources

Tag archives for Jennifer Grandis

Never Giving Up: UPMC, Pitt Researchers Receive Grants Totaling $800,000 from V Foundation

PITTSBURGH, Oct. 21, 2014 – Researchers from the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, have been awarded a grant from the V Foundation for Cancer Research to study gene mutations in patients whose head and neck cancer was caused by human papillomavirus (HPV) in hopes of finding a more effective, less toxic therapy for […]

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Recurrent Head and Neck Tumors Have Gene Mutations That Could be Vulnerable to Cancer Drug

SAN DIEGO, April 4, 2014 – An examination of the genetic landscape of head and neck cancers indicates that while metastatic and primary tumor cells share similar mutations, recurrent disease is associated with gene alterations that could be exquisitely sensitive to an existing cancer drug. Researchers from the University of Pittsburgh Cancer Institute (UPCI) and […]

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No ‘Brakes’ — Pitt Study Finds Mechanism for Increased Activity of Oncogene in Head and Neck Cancers

PITTSBURGH, Jan. 6, 2014 – The increased activation of a key oncogene in head and neck cancers could be the result of mutation and dysfunction of regulatory proteins that are supposed to keep the gene, which has the potential to cause cancer, in check, according to a new study led by researchers at the University […]

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Pitt Cancer Institute Researchers Say Decoy Shows Promise as Cancer-Fighter in Novel Phase 0 Trial

PITTSBURGH, August 10, 2012 – A critical protein that had been deemed “undruggable” can be effectively targeted by using a decoy to fool the body into a cancer-fighting response, according to researchers at the University of Pittsburgh Cancer Institute (UPCI) and the University of Pittsburgh School of Medicine. In a report in the August issue […]

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