The UPMC Heart and Vascular Institute was well-represented at the American Heart Association’s Scientific Sessions in Anaheim, CA on Saturday, Nov. 11 – Wednesday, Nov. 15. Faculty research was presented in both oral and abstract presentations including:

Saturday, November 11, 2017

Session RESS.CVS.02 – Main Event: Outcomes of Cardiac Arrest Survivors With ICDs

Rehabilitation for Cardiac Arrest Survivors with ICDs

Presented by: Jon C. Rittenberger


Session RESS.CVS.06 – Main Event: Prognostication After Resuscitation

Prognostication After Major Trauma and TBI

Presented by: Lori A. Shutter


Sunday, November 12, 2017

Session SA.JS.783 – Innovation in Cardiac Surgery: From Imaginative Research to Transformative Clinical Therapy (AHA/The Society of Thoracic Surgeons Joint Session)

Should Bicuspid Valves Ever Be Repaired?

Presented by: Thomas Gleason


Session QU.APS.01 – Quality of Care: Acute and Chronic CAD

Predictors of Emergency Medical Personnel’s Decision to Transmit or Not to Transmit the Prehospital 12-Lead ECG of Patients With Suspected Acute Myocardial Infarction

Presented by: Amber DeSantis, Parker Landis, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti


Session NR.APS.02 – Monitoring and ICDs: Patients With ACS and CABG

The Prevalence of Secondary Repolarization Abnormalities  Confounding the Electrocardiographic Diagnosis of Acute Myocardial Ischemia in Patients Presenting With Chest Pain

Presented by: Diana Rivero, Mohammad Alhamaydeh, Christian Martin-Gill, Clifton Callaway, Barbara Drew, Salah S Al-Zaiti


Time of Day and Day of Week Variations in Chest Pain Encounters at the Prehospital Setting

Presented by: Mohammad Alhamaydeh, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti

Incidence and Predictors of Delaying Seeking Emergent Medical Care Among Patients With Suspected Acute Coronary Syndrome

Presented by: Stephanie Frisch, Christian Martin-Gill, Mohammed Alrawashdeh, Clifton Callaway, Salah Al-Zaiti


Session CH.APS.01 – Fetal Cardiology

Fetal Hemodynamics Predict Postnatal Regional and Microstructural Brain Alterations in Complex Congenital Heart Disease

Presented by: Jodie K. Votava-Smith, Jay D. Pruetz, Nhu Tran, Vincent Lee, Hollie Lai, Vincent J. Schmithorst, Lisa B. Paquette, Ashok Panigrahy


Session CH.RFO.03 – Transitional Research in CHD

Altered Placental Bold Signal is Associated With Reduced Fetal Brain Functional Connectivity in Congenital Heart Disease

Presented by: Vidya Rajagopalan, Vincent K Lee, William Reynolds III, Alex El-Ali, Jenna Schabdach, Julia Wallace, Alexandria Zahner, Rafael Ceschin, Jodie Votava-Smith, Jacqueline Weinberg, Vincent J Schmithorst, Ashok Panigrahy


Session HF.APS.08 – Heart Failure and Cardiomyopathies: General Topics IIII

Are Echocardiogram and Magnetic Resonance Imaging (MRI) Comparable in Measuring Maximal Septal Thickness in Children With Hypertrophic Cardiomyopathy (HCM)?

Presented by: Sonya Kirmani, Pamela K Woodard, Ling Shi, Charles E Canter, Steven D Colan, Elfriede Pahl, Jeffrey A Towbin, Steven A Webber, Joseph W Rossano, Melanie D Everitt, Kimberly M Molina, Paul F Kantor, John L Jefferies, Brian Feingold, Linda J Addonizio, Stephanie M Ware, Wendy K Chung, Jean A Ballweg, Teresa M Lee, Hiedy Razoky, Jason D Czachor, Fatima I Lunze, Edward Marcus, James D Wilkinson, Steven E Lipshultz


Session CH.RFO.03 – Translational Research in CHD

Identification of a Novel TPM1 Mutation in Congential Atrial Septal Defect With Autosomal Dominant Inheritance

Presented by: Polakit Teekakirikul, Wenjuan Zhu, Michael X Wang, Amanda M Smith, Honglan Gou, Abha Bais, Omar Khalifa, Maliha Zahid, Stephanie M Ware, Brian Feingold, Cecilia W Lo



Session IN.APS.05 – Percutaneous Non-Coronary Cardiac Intervention

Denovo Pulmonary Hypertension After Transcatheter Aortic Valve Replacement is Associated With Higher Mortality – The Importance of Continued Assessment

Presented by: Joao L Cavalcante, Islam Abdelkarim, Jeffrey Xu, Michael Sharbaugh, Andrew D Althouse, Dustin Kliner, Ibrahim Sultan, Frederick Crock, Matthew E Harinstein, William E Katz, Joon S Lee, John T Schindler, Thomas G Gleason


Session RESS.AOS.11A – Oral Abstracts-Cardiac Arrest Epidemiology

Long-Term Outcomes Disparities in Survivors of Cardiac Arrest 

Presented by: Patrick J Coppler, Jonathan Elmer, Jon C Rittenberger, Clifton W Callaway, David J Wallace


Session Va.APS.01 – Latest in Pulmonary Embolism, Injury and Non Group 1 Pulmonary Hypertension

Effect of Remodulin in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction (PH-HFpEF)

Presented by: Jian Hu, Ana L Mora, Mark T Gladwin, Yen-Chun Charly Lai


Monday, November 13, 2017

Session SA.APS.05 – Thoracic Aortic Surgery II

Characterization of Type B Acute Aortic Dissection Patients With Presenting Spinal Cord Ischemia

Presented by: Jonathan Silverberg, Thomas G Gleason, Maral Ouzounian, Reed E Pyeritz, Marek P Ehrlich, Takeyoshi Ota, Eduardo Bossone, Stuart Hutchison, Truls Myrmel, Mark D Peterson, Gilbert R Upchurch Jr, Daniel G Montgomery, Eric M Isselbacher, Christoph A Nienaber, Kim A Eagle, Himanshu J Patel


Session GE.APS.03 – Genetics and Genomics Using Big Data

GWAS Identifies GPC6 as a Novel Predictor of Arrhythmia in Heart Failure

Presented by: Haider Mehdi, Ryan L Boudreau, Rebecca Gutmann, Patrick Breheny, Gina M Morgan, Alexander M Greiner, Heather L Bloom, Alaa Shalaby, Raul Weiss, Samuel C Dudley, Samir Saba, Dennis M McNamara, Madhurmeet Singh, Steven A Lubitz, Patrick T Ellinor, Barry London



Session VA.AOS.1970 – Not Home Alone: Mechanistic Insights into Associated Pulmonary Hypertension

Proinflammatory Monocytes and Fibrotic Alveolar Macrophages Are Associated With Progression of Pulmonary Arterial Hypertension in a Primate Model of Human Immunodeficiency Virus Infection

Presented by: Finja Schweitzer, Rebecca Tarantelli, Marc Simon, Whitney Rabacal, Emily Rayens, Karen Norris


Session AT.APS.22 – Vascular Science and Hypertension: Experimental

Longitudinal Assessment of Hemodynamic Changes in a NonHuman Primate Model of Human Immunodeficiency Virus Associated Pulmonary Arterial Hypertension

Presented by: Rebecca A Tarantelli, Marc A Simon, Rebecca Vanderpool, Ian Christman, Finja Schweitzer, Heather Kling, Toni Ann Zullo, Eoin J Carney, Brian Lopresti, Karen A Norris


Session HF.APS.18 – CHF/Cardiomyopathy: Novel Insights

NAT2 Genotype and Outcomes in the Genetic Sub-Study of the African American Heart Failure Trial (AHeFT)

Presented by: Barry E Bleske, Hao-Jie Zhu, Karen Hanley-Yanez, Indrani Halder, Dennis M McNamara


Session RESS.APS.03.07 – ReSS Poster Session Day 3, Section 07

Clinical Outcomes and Mortality Impact of Hyperbaric Oxygen Therapy in Patients With Carbon Monoxide Poisoning

Presented by: Jason J Rose, Seyed M Nouraie, Marc C Gauthier, Anthony F Pizon, Melissa I Saul, Michael P Donahoe, Mark T Gladwin


Session RESS.APS.03.13 – ReSS Poster Session Day 3, Section 13

Hypothermic to Ischemic Ratio as a Predictor of Good Functional Outcome From Out-of-Hospital Cardiac Arrest in the Resuscitation Outcomes Consortium Amiodarone Lidocaine or Placebo Study

Presented by: Kelly N Sawyer, Andrew Humbert, Brian G Leroux, Graham Nichol, Peter J Kudenchuck, Mohamud R Daya, Brian Grunau, Henry E Wang, Joseph P Ornato, Jon C Rittenberger, Tom P Aufderheide, Lynn Wittwer, M Riccardo Colella, Michael Austin, Takahisa Kawano, Debra Egan, Neal Richmond, Veer D Vithalani, Damon Scales, Andrew J Baker, Laurie J Morrison, Michael C Kurz


Session RESS.APS.03.11 – ReSS Poster Session Day 3, Section 11

Times to Recovery in Individual Domains of the Cerebral Performance Category-Extended

Presented by: Katharyn L Flickinger, Melissa J Repine, Allison C Koller, Margo B Holm, Elizabeth R Skidmore, Clifton W Callaway, Jon C Rittenberger


Session RESS.APS.03.13 – ReSS Poster Session Day 3, Section 13

Delayed Left Atrial Decompression is Associated With Prolonged Duration of Veno-arterial Extracorporeal Membrane Oxygenation Support: Results of a Multicenter Pediatric Interventional Cardiology Early Career Society (PICES) Study

Presented by: Jeffrey D. Zampi, Fares Alghanem, Sunkyung Yu, Ryan Callahan, Christopher L. Curzon, Jeffrey W. Delaney, Robert G. Gray, Carrie E. Herbert, Ryan A. Leahy, Ray Lowery, Sara K. Pasquali, Priti M. Patel, Diego Porras, Shabana Shahanavaz, Ravi R. Thiagarajan, Sara M. Trucco, Mariel E. Turner, Surendranath R. Veeran Reddy, Shawn C. West, Wendy Whiteside, Bryan H. Goldstein


Session RESS.AOS.14 – Dickinson W. Richards Memorial Lecture

Epidemiology of Out-of-Hospital Cardiac Arrest Within the Resuscitation Outcomes Consortium From 2011 to 2015: Improved Survival Though Site Differences Persist

Presented by: Dana M Zive, Robert Schmicker, Mohamud Daya, Peter Kudenchuk, Jon C Rittenberger, Tom Aufderheide, Gary Vilke, Jim Christenson, Jason Buick, Ken Kaila, Susanne J May, Thomas Rea, Laurie J Morrison


Session SA.CVS.762 – Hot Topics in Cardiovascular Surgery

Toward Precision/Molecular Medicine: Determinants of Surgical Decision Making in Bicuspid Valve Disease

Presented by: Thomas Gleason


Session LB.APS.09 – Clinical Risk Factors and Biomarkers in Risk Prediction

Evaluating the Diagnostic Accuracy of Clinical Risk Scores to Detect Acute Coronary Syndrome in Patients Evaluated at the Emergency Department for a Chief Complaint of Chest Pain

Presented by: Ziad Faramand, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti


Session HF.APS.25 – New Insights into Heart Failure Biomarkers

Interaction of G-Protein Beta 3 Subunit (GNB3) and G-Protein Receptor Kinase 5 (GRK5) Genotypes Impacts Heart Failure Outcomes in African Americans

Presented by: Amber E Johnson, Karen Hanley-Yanez, Clyde W Yancy, Anne L Taylor, Arthur M Feldman, Dennis M McNamara


Session GE.APS.07 – Genomics of Cardiovascular Risk

Contribution of ABCA1 Genetic Variation to Plasma Lipid Levels in Non-Hispanic White Americans

Presented by: Vipavee Niemsiri, Xingbin Wang, Zaheda H Radwan, Dilek Pirim, Indrani Halder, Steven E Reis,  John E Hokanson, Richard F Hamman, M Michael Barmada, Eleanor Feingold, F Yesim Demirci, M Ilyas Kamboh


Session CH.APS.13 – Congenital Heart Disease and Pediatric Cardiology: General Topics

Impaired Pre-Operative Cerebral Autoregulation is Associated With Functional Brain Dysmaturation in Neonatal Congenital Heart Disease

Presented by: Jodie K Votava-Smith, Vincent J. Schmithorst, Nhu Tran, Sadaf Soleymani, Justin Abbott, Vincent Lee, Sylvia del Castillo, Hollie A. Lai, Lisa B. Paquette, Ashok Panigrahy


Session EA.RFO.04 – State of the Art: Topical Trial Results From Electrophysiology

Wealth Brings Health: Annual Income is Associated With Health-related Quality of Life in Atrial Fibrilation

Presented by: Emily N Guhl, Andrew D Althouse, Michael Sharbaugh, Courtney L Schlusser, Jared W Magnani  


Session HF.APS.16 – Heart Failure and Cardiomyopathies: General Topics IV

Sex Differences and Outcomes of Heart Failure Admissions Stratified by Left Ventricle Ejection Fraction

Presented by: Ahmad Masri, Andrew D Althouse, Gavin Hickey, Jeffrey McKibben, Ravi Ramani, Michael Mathier, Joon Lee, Oscar Marroquin, Suresh Mulukutla


Tuesday, November 14, 2017

Session HF.APS.40 – Insights into CHF Risk Factors and Outcomes

Cytokine Elevations and Outcomes in Peripartum Cardiomyopathy

Presented by: Dennis M McNamara, Karen Hanley-Yanez, Penelope Morel, Charles McTiernan


Session HF.APS.33 – Novel Insights Into the Diagnosis and Prognosis of Cardiomyopathy and Heart Failure

Cellular Immune Activation and Breastfeeding in Peripartum Cardiomyopathy

Presented by: Agnes Koczo, Amy Marino, Arun Jeyabalan, Uri Elkayam, Leslie Cooper, James Fett, Charles McTiernan, Penelope Morel, Karen Hanley-Yanez, Dennis McNamara


Session: IM.CVS.732 – TAVR: Imaging Highlights

Echocardiography Assessment of Critical Aortic Stenosis prior to TAVR

Presented by: Joao L Cavalcante


Session ST.AOS.888 – Stroke Oral Abstracts

Biventricular Cardiac Dysfunction in Neurocardiac Injury Assessed by Strain Imaging is Associated With In Hospital Mortality in Subarachnoid Hemorrhage

Presented by: Nobuyuki Kagiyama, Masataka Sugahara, Nina E. Hasselberg, Eliabeth A. Crago, Theodore F. Lagattuta, Khalil Moh’d Yousef, Marilyn T. Hravnak, John Gorcsan III


Session IM.APS.19 – Echocardiography: Hypertension, Coronary Artery Disease, and Function

Biventricular Strain as a New Marker of Severity of Neurocardiac Injury in Patients With Subarachnoid Hemorrhage

Presented by: Nobuyuki Kagiyama, Masataka Sugahara, Nina E. Hasselberg, Eliabeth A. Crago, Theodore F. Lagattuta, Khalil Moh’d Yousef, Marilyn Hravnak, John Gorcsan III


Session EP.RFO.42 – AHA’s Life Simple 7 and 2020 Goals

The AHA Life Simple 7: An Assessment Using the Behavorial Risk Factor Surveillance System 2011-2015

Presented by: Andrew D Althouse, Michael S Sharbaugh, Floyd W Thoma, Joon Sup Lee, Vince M Figueredo, Suresh R Mulukutla


Session CH.CVS.682 – VAD to Transplant: Challenges and Insights

Are we too sensitive? Challenges With managing the Sensitized Patient

Presented by: Brian Feingold


Session WS.APS.04 – Race, Sex, SES: Disparities in Cardiovascular Care

African-American Ethnicity, Risk Variables, Coronary Artery Disease, and Long-Term Prognosis in Women: The National Heart, Lung, and Blood Institute Sponsored Women’s Ischemia Syndrome Evaluation Study

Presented by: Pankaj Malhotra, Galen Cook-Wiens, Carl J Pepine, Eileen M Handberg, Steven E Reis, Nathaniel Reichek, Vera Bittner, Sheryl F Kelsey, Reddy Sailaja Marpuri, George Sopko, C Noel Bairey Merz